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Eric Dane
After becoming enamored with performing in high school, Eric Dane became another LA transplant doing the Hollywood hustle. He started small — guest parts on a string of series like "Saved By The Bell" and "Married … With Children" — before being offered slightly meatier roles on the short-lived 2001 medical drama "Gideon's Crossing" (where he met his longtime girlfriend Lara Flynn Boyle during a crossover episode with "The Practice") and "Charmed" (2003-04). But it wasn't until he stepped out of that second season hot shower on "Grey's Anatomy" that he truly earned his place as a big-time small-screen stud. He