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Kathy Griffin
The Emmy-winning comedian was teased as a girl for her ginger locks and freckles, but it is she that got the last laugh as she became a famous funny girl, talk show host, Grammy nominee, reality star and best-selling author. She made a career out of mocking celebrities and the silly things they do as well as poking fun at herself. She moved to LA after some high school theater and a few junior college classes to study acting at the Lee Strasberg Institute and join The Groundlings troupe. Her one-woman show encouraged HBO to give her a comedy special