Guy Ritchie
The English auteur struggled with dyslexia and attended a number of schools before being asked to leave for good at 15 after being caught using drugs. After a series of low-level jobs like bricklayer and bartender, he caught a break working as a runner for a friend who directed commercials when he was 25 and it wasn't long before he was helming ads and music videos himself. His first film was a short in 1995, "The Hard Case," but it would take three more years before he'd get to release his brilliant first feature "Lock, Stock and Two Smoking Barrels."